A new clinical study reports that cannabis acts as a bronchodilator, meaning that it dilates the bronchi and bronchioles, increasing airflow to the lungs. This peer-reviewed study was published in the Journal of Pharmacology and Experimental Therapeutics. It claims that cannabinoids protect the lungs from constriction and can be quite helpful for asthma patients.
The study compared the effects of six cannabinoids – THC, CBD, CBG, CBC, CBD-A, and THC-V – on contractions of the guinea pig-isolated trachea and bronchoconstriction induced by nerve stimulation in anesthetized guinea pigs. A team of researchers at the King’s College London, led by Raj Makwana, discovered the following:
Only Δ(9)-tetrahydrocannabinol [THC] inhibited TNF-α-enhanced vagal-induced bronchoconstriction, neutrophil recruitment to the airways, and citric acid-induced cough responses.
Tetrahydrocannabivarin [THC-V] partially inhibited the TNF-α-enhanced nerve-evoked contractions, whereas the other cannabinoids were without effect. (Source)
This is great news for those with asthma, who often suffer from bronchoconstriction, the constriction of the airways in the lungs, nose and mouth due to the tightening of surrounding muscles. Because of this, an asthma attack limits a person’s oxygen intake. Low-level inflammation can also be found in bronchi and bronchioles of asthma sufferers.
Over the last few decades, we’ve come to better understand the role of cannabinoids on the human body. Cannabinoid receptors are present throughout the body. This explains why people can benefit from cannabis in so many different ways.
(Article Source & Credit: Waking Times)